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我院中西医结合科风湿免疫中心聘请美国俄勒冈州波特兰 健康与科学大学初从秋教授为客座教授
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  科室动态-->>>中西医结合科风湿病专科 更新时间:2016-12-06
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    11月24日下午,美国俄勒冈州波特兰 健康与科学大学初从秋教授受聘我院客座教授仪式在教学楼五楼第二会议室举行。郭忠诚院长为初从秋教授颁发了证书。初从秋教授现任美国风湿病学会学术会议组织计划委员会委员 (负责基础科学部分)、美国西北风湿病学会主席,学术会议组织计划委员会委员。受聘仪式上,方勇飞主任介绍了初从秋教授的基本情况。随后,初从秋教授就目前风湿免疫病的前沿进展做了报告。讲座结束后,与会人员进行了热烈的互动交流。最后,初从秋教授表示将加强与中西医结合科风湿免疫中心研合作,互利双赢,为学科发展和我院建设作出更多的贡献。
初从秋教授工作经历:
1983-1988  中国医学科学院/北京协和医院 – 住院医生/硕士生
1988 -1992  肯尼迪风湿病研究所  PhD     英国伦敦
1983-1997  肯尼迪风湿病研究所  博士后  英国伦敦
1997-2000  特鲁多研究所博士后 美国纽约州
           萨拉纳克湖 (Saranac Lake)
2000-2004  (密歇根)州立韦恩大学医学院 住院医生 美国密歇根州
           底特律
2004-2006  华盛顿大学医学院风湿病专科医生培训 美国华盛顿州
           西雅图
2006-2008  华盛顿大学医学院风湿科风湿科医生, 助理教授
2008-      俄勒冈医科大学附属医院风湿科医生, 助理/副教授
           美国俄勒冈州波特兰
代表文章:
1. Chu CQ, Field M, Feldmann M, Maini RN. Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum. 1991, 34(9):1125-32. (this paper was selected by the Editor-in-Chief and the editorial board members (for 1990 – 1995) as one of the most important articles and one of the most cited articles published by Arthritis and Rheumatism, 1990-1995 – see Peter Schur, A&R,58(2), suppl. S89-S91). ) (Citation count: 525)
2. Chu CQ, Londei M. Induction of Th2 cytokines and control of collagen-induced arthritis by nondepleting anti-CD4 Abs. J Immunol. 1996,157(6):2685-9
3. Chu CQ, Field M, Andrew E, Haskard D, Feldmann M, Maini RN.Detection of cytokines at the site of tuberculin-induced delayed-type hypersensitivity in man. Clin Exp Immunol. 1992,90(3):522-9.
4. Chu CQ, Londei M. Differential activities of immunogenic collagen type II peptides in the induction of nasal tolerance to collagen-induced arthritis. J Autoimmun. 1999,12(1):35-42.
5. Katsikis PD, Chu CQ, Brennan FM, Maini RN, Feldmann M. Immunoregulatory role of interleukin 10 in rheumatoid arthritis. J Exp Med. 1994, 179(5):1517-27
6. Chu CQ, Wittmer S, Dalton DK. Failure to suppress the expansion of the activated CD4 T cell population in interferon-gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J Exp Med. 2000, 192(1):123-8. (was selected as a “of special interest” paper, in Current Opinion in Immunology, 12:494-5). (Citation count: 338)
7. Dalton DK, Haynes L, Chu CQ, Swain SL, Wittmer S. Interferon-gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J Exp Med.  2000, 192(1):117-22 (was selected as a “of special interest” paper, in Current Opinion in Immunology, 12:491). (Citation count: 307)
8. Chu CQ, Song Z, Mayton L, Wu B, Wooley PH. IFNgamma deficient C57BL/6 (H-2b) mice develop collagen induced arthritis with predominant usage of T cell receptor Vbeta6 and Vbeta8 in arthritic joints. Ann Rheum Dis. 2003,62(10):983-90.
9. Chu CQ, Swart D, Alcorn D, Tocker J, Elkon KB.Interferon-gamma regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17. Arthritis Rheum. 2007, 56(4):1145-1151.
10. Morita Y, Ismail DM, Keith B. Elkon KB, Chu CQ. Dichotomous response to transforming growth factor β after T cell receptoractivation by naive CD4+ T cells from DBA/1 mice: enhanced retinoic acid receptor-related orphan nuclear receptor γt expression yet reduced FoxP3 expression.Arthritis Rheum. 2011, 63: 118-26.(was evaluated by Faculty of 1000 Medicine as a “Must Read (FFa 8)” paper. http://f1000.com/8563958)
11. Yomogida K, Chou Y, Pang J, Baravati B, Maniaci BJ, Wu S, Zhu Y and Chu CQ. Streptavidin suppresses T cell activation and inhibits IL-2 production and CD25 expression. Cytokine, 2012, 58:431-6.
12. Song P, Chou YK, Zhang X, Meza-Romero R, Yomogida K, Benedek G,Chu CQ. CD4 aptamer-RORγt shRNA chimera inhibits IL-17 synthesis by human CD4(+) T cells. Biochem Biophys Res Commun. 2014,452(4):1040-5.
13. Li Y, Liu Y, Chu CQ. Th17 Cells in Type 1 Diabetes: Role in the Pathogenesis and Regulation by Gut Microbiome. Mediators Inflamm. 2015;2015:638470. doi: 10.1155/2015/638470. Epub 2015 Dec 30.
14. Lin H, Song P, Zhao Y, Xue LJ, Liu Y, Chu CQ. Targeting Th17 Cells with Small Molecules and Small Interference RNA. Mediators Inflamm. 2015;2015:290657. doi: 10.1155/2015/290657. Epub 2015 Dec 17.
 
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